Pharmaceutical Intermediates

Borregaard has manufactured fine chemicals for pharmaceutical companies worldwide for more than fifty years. Our production capacity and strong market position are continuously improving, allowing us to keep up with market demands.

Our core expertise is in contrast media and advanced pharmaceutical intermediates. The opportunities our products bring to the market are endless.

Borregaard focuses on core capabilities. This allows us to be highly competitive while meeting the demands of the modern pharmaceutical industry.

We pride ourselves on our transparency and commitments to our customers, many of whom have been with us since we started. We believe this is proof of our excellent customer service and high, and consistent quality products. It inspires us to continue to strive for improvement.

Our core products

Borregaard ensures customer loyalty with a tightly controlled manufacturing process that yields stable, high-quality products.

Our pharmaceutical intermediates mainly serve the contrast media market though we hold supply positions to other demanding areas.

Our products can be delivered in volumes and packaging tailored to your needs. However, you may prefer delivery in ISO containers as these can be heat regulated and ensure the stability of our products.

Polyimide Monomers

As an attractive dielectric material, Polyimide Monomers have been widely used in the field of electronics, aerospace, and automobiles fulfilling the increasing need for materials that can perform well under harsh conditions, such as elevated temperatures. Polyimides are an important class of step-growth polymers due to their high-temperature stability, mechanical properties, and superior chemical resistance.

Explore Polyimides (PI) in detail along with their key properties like mechanical, thermal, electrical, etc., and understand what makes them an ideal choice in high-end engineering applications.

Polyimides (PI) are high-performance polymers of imide monomers that contain two acyl groups (C=O) bonded to nitrogen (N). These polymers are known for their high-temperature performance in the 400-500°C range as well as chemical resistance.

They are used to replace the conventional use of glass, metals, and even steel in many industrial applications.

Polyimides offer excellent mechanical properties and thus find use in applications that demand rugged organic materials, e.g.

High-temperature fuel cells

Flat-panel display

Aerospace applications

Chemical and environmental industries

As well as various military applications

Key Facts about Acrylate Monomers

butyl-methacrylate-303957-elite acrylic ester copolymerization is an important technique to achieve systematic tailoring of properties required in a broad range of end-use applications. ; Glacial acrylic acid (GAA) and glacial methacrylic acid (GMMA) are acrylate monomers ;used to functionalize acrylic copolymers.

The short-chain acrylic monomers like methyl methacrylate and other monomers like styrene produce harder, more brittle polymers, with high cohesion and strength characteristics. ; The long-chain monomers like butyl acrylate and 2-ethyl hexyl acrylate enable soft, flexible, tacky polymers with lower strength characteristics. Monomers like ethyl acrylate, butyl methacrylate, and vinyl acetate contribute more intermediate glass transition and hardness values. ; Co-monomers such as acrylonitrile and (meth)acrylamide, can improve solvent and oil resistance.

By managing the comonomer ratios and the glass transition temperatures, chemists can balance hardness and softness, tackiness and block resistance, adhesive and cohesive properties, low-temperature flexibility, strength and durability, and other key properties to facilitate end-user goals.

Advancements in film mechanical properties; chemical, water, and abrasion resistance; durability; adhesive properties; and solvent resistance have driven the growth of acrylic copolymers, especially in water-borne technologies. ; A major contributor to these performance enhancements has been new polymer crosslinking chemistries. Exemplary of this trend is the use of diacetone acrylamide functional monomer, which can be incorporated into acrylic systems to afford controlled crosslinkability.

Deuterated Compounds: Optimizing Drug Stability

A deuterated drug is a small molecule in which one or more of the hydrogen atoms are replaced by deuterium. As deuterium and hydrogen have nearly the same physical properties, deuterium substitution is the smallest structural change that can be made to a molecule.

Advantages:

As a deuterated drug is broken down slower, it stays longer in the body and hence requires less frequent dosing (in terms of strength & regimen)

Because of the kinetic isotope effect, deuterated drugs have significantly lower rates of metabolism, and hence a longer half-life

Deuterium replacement may also lower toxicity by reducing toxic metabolite formation

In addition, the deuterated drug is more stable in the presence of other drugs, resulting in reduced drug-drug interactions

A major potential advantage of deuterated compounds ;is the possibility of faster, more efficient, and less costly clinical trials, because of the extensive testing the non-deuterated versions have previously undergone. ;